volker schulz and Rudolf Hansel
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 John's wort(E)
A
24
715
252
6358
Aspecton Saft N (L)
Thyme (E)
B
25
718
250
1777
Tussamag
Thyme (E)
B
26
761
234
1118
Hustensaft N (L)
Bronchicum Elixier N (L) Primrose root (E)
B
27
782
226
1375
Thyme (E)
Laif 600 (T)
St. |
| John's wort (E)
Lemon balm leaves (E)
Eucabal Balsam S
Eucalyptus oil
B
59
1394
118
686
Pine needle oil
Hyperforat (CT)
St. |
Earl L. Mindell, R.Ph., Ph.D.
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 The best way to take kava is powdered, in a capsule or as an extract.
St. john's wort (Hypericum perforatum) is a medicinal plant with a beautiful yellow flower that's been used by the Chinese, the Greeks, the Europeans and the American Indians for centuries to treat heart disease, anxiety, insomnia and depression. In a study of 105 patients who had symptoms of mild to moderate depression, half the patients took 300 mg of St. john's wort extract three times a day for four weeks, and the other half took a placebo. Some 67 percent of the group taking the St. |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| Before you resort to prescription drug sedatives, try some of the natural antianxiety remedies such as kava and St. john's wort. (See pages 332-333 in Chapter Fourteen for reassuring information on kava if you're concerned about recent links between kava and liver damage.)
Your first attempts at reassuring and calming a stroke victim should be the best sedatives of all: loving, supportive family and friends, gentle massage, humor, beautiful music, a good view out the window, good nutrition, and competent medical care and physical therapy. |
Sheldon Saul Hendler and David Rorvik
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 HERBS
Saint John's wort: Theoretically, concurrent use of 5-HTP and Saint john's wort may both potentiate the possible antidepressant activity of the herbal product and increase the risk of adverse reactions.
OVERDOSAGE
There are no overdosage reports in humans. There are reports of overdosage and subsequent serotonin-like syndrome in dogs. Some of these overdosages resulted in death to the animals.
DOSAGE AND ADMINISTRATION
Supplemental 5-HTP is not recommended. In Europe, a combination of 5-HTP with carbidopa is available, and this combination appears to have a safer profile. |
David Hoffman, FNIMH, AHG
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 Herbs for Children's Skin Problems
Calendula officinalis (calendula) Galium aparine (cleavers) Hypericum perforatum (St. john's wort) Plantago major (plantain)
Stellaria media (duckweed) Trifolium pratense (red clover) Urtica dioica (nettle) Viola tricolor (heartsease)
DIAPER RASH
An irritation of the skin caused by dampness, the interaction of urine (and ammonia from the urine), and feces. A rash is any skin swelling (bumps) or blotches on a baby (can be red, skin-colored, or slightly lighter or darker than skin color). |
Mark Stengler, N.D.
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 People took either 1,800 mil-
Anxiety
St. john's wort has been found to be as effective as pharmaceuticals in treating anxiety. c*** Bruises, Burns, and Wounds
St. john's wort has a long history of use for the treatment of bruises, burns, and wounds. The oil is applied topically and provides soothing relief as well as prevents secondary bacterial infections. It also helps to relieve nerve injuries and nerve pain. European herbalists also use the oil for the treatment of eczema.
^ Depression
St. |
Nicola Reavley
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 Herbal medicine and carpal tunnel syndrome
St. john's wort {Hypericum perforatum) is a useful herb for joint, muscle, or nerve trauma and it has demonstrated anti-inflammatory effects in scientific studies. Rubbing oil of St. john's wort on the wrist may be useful in relieving the symptoms of carpal tunnel syndrome. Ginger {Zingiber officinale) is also anti-inflammatory and may also be useful if applied to the affected area. See page 384 for more information on these herbs and the precautions that may be necessary. |
The Life Extension Editorial Staff
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 President Emeritus of Seattle's Bastyr University, author of Total Wellness and coauthor of Encyclopedia of Natural Medicine, recommends 200 mg twice a day for 2 days, 400 mg twice a day on days 3 through 9, then 400 mg three times a day on days 10 through 19, followed by 400 mg four times daily thereafter.
St. john's wort (Hypericum perforatum)
In Germany, where it is covered by health insurance as a prescription drug, some 20 million people take hypericum for depression. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
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| Baseline HDS
Dose
Duration
Responder rate
Responder rate
(mg/day)
(weeks)
(St john's wort )
(placebo)
Trials comparing St john's wort with placebo
Halama24
50
18.0
1.08
4
10/25
0/25
Hansgren et al25
72
20.4
2.7
4
27/34
9/38
Harrer & Sommer26
120
20.9
0.75
CD
22/58
9/58
Hubner et al27
40
12.4
2.7
4
14/20
9/20
Quandt et al28
88
17.3
0.75
4
29/44
3/44
Reh et al29
50
20.0
1.0
CO
20/25
11/25
Schmidt & Sommer30
65
16.4
1.08
6
20/32
6/33
Schmidt et al31
40
29.5
0.75
4
15/25
3/24
Sommer & Harrer32
105
15.8
2. |
Thomas Bartram
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 Combine: 5 drops each: Tincture Arnica, Tincture Calendula (Marigold), Tincture Hypericum (St john's wort), to half a glass water (100ml). Dose: one teaspoon hourly to help dissipate shock and mobilise the body's recuperative powers.
Skullcap tea. For nerve weakness. Local. To restore flesh which has been abnormally stretched and bruised. Bathe with weak tincture Arnica, St john's wort or decoction Comfrey root.
Vitamins. A. B-complex. B12. C (500mg). E (l,000iu) daily. Mineral: Zinc.
Note. Do not take a surgeon's qualifications for granted. |
James A. Duke, Ph.D.
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 John's wort needs 4 to 6 weeks to impart its mood-elevating effects.
St. john's wort is a lovely plant that produces bright yellow flowers with purplish dots. Poetically, the dots symbolize the blood of St. John, because the plant blooms around St. John's Day, June 24. hop (humulus lupulus). The herb best known for giving beer a bitter taste is also a potent stress and anxiety reducer. Folktales abound of hop pickers falling asleep on the job. This comes as no surprise, since hop is a botanical relative of marijuana. It's not psychoactive, however. |
| John's Wort
Hypericum perforatum
St. john's wort is a short-lived perennial that may need to be replanted every couple of years. To speed the germination of seeds, I suggest putting them in a plastic bag with some sand and refrigerating them for 2 weeks. Then press them into a flat of moist, very sandy soil.
If you live in a region with cold winters, plant the seedlings in the spring. In milder climates, plant them in the fall. They need well-drained soil and do best in full sun, though they'll tolerate sparse shade. Place the seedlings 24 inches apart, with 24 inches between rows. |
Heather Boon, BScPhm, PhD and Michael Smith, BPharm, MRPharmS, ND
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 In this study, neither treatment (St. john's wort nor fluoxetine) was found to be significantly better than placebo on the two primary outcome measures of the trial (change in Hamilton Depression total score and rates of full response).72 This study also stimulated much discussion. |
| Traditional Use
St. john's wort has been recognized in the West as having medicinal properties since the classical period. The name itself has been associated with a colorful mythology involving Saint John the Baptist, and there are varied customs using the plant as a talisman to ward off misfortune. It was mentioned in the texts of Hippocrates, Pliny, and Galen as helpful for wound healing, pain, and as a diuretic. The use of this herb continued though the Renaissance and Victorian eras,13 6 when it was also used as a treatment for emotional and nervous complaints. Oil infused with St. |
Kenny Ausubel
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 St. john's wort has made headlines for its efficacy against depression. A meta-analysis of twenty-three German studies found the herb more effective than synthetic antidepressant drugs such as Prozac and Zoloft for cases of mild depression.7 German physicians now prescribe St. john's wort at least seven to one over these synthetic drugs. U.S. sales netted about $400 million in 1997, though still a distant second to Eli Lilly's Prozac sales of $2.5 billion in 1996.8 The NIH has now started research on this plant. |
Patrick Holford
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 Maintenance 100 meg a day.
St. john's wort (hypericum)
Particularly good for anything that penetrates the skin, such as a wound or skin infection. It is a good general tonic for the immune system.
Fighting injections 50 to 500 mg a day. Tea tree oil
An Australian remedy with antiseptic properties. Great for rubbing on the chest or using in the bath, steam inhaling, or to help keep mosquitoes away. Take as instructed on the bottle. Lozenges are also available.
Zinc
The most important immune-boosting mineral. There is no doubt that it helps fight infections. |
Mark Stengler, N.D.
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| Depression
St. john's wort has been the subject of some of the best and most intensive clinical and scientific research among all the herbs in the world. I find that it is helpful in about 70 percent of people who take it for depression. This is quite a high response rate, whether a pharmaceutical or ligrams of St. john's wort or 150 milligrams of imipramine for 6 weeks. Improvements in depression were about equal. Again, side effects were more common in those taking imipramine. This study was important because it examined people with moderate to severe depression. |
Donald R. Yance, j r.,C.N., M.H., A.H.G., with Arlene Valentine
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 John's Wort [Hypericum perforatum)
St. john's wort is a wonderful nervine, especially indicated for mild forms of depression with poor circulation and nerve injury. It can be used both internally and externally for nerve trauma. A specific for postoperative brain tumor surgery, it helps in three different ways:
1. It promotes healing from trauma and inflammation.
2. It helps with postoperative depression.
3. It acts as an inhibitor of neoplastic activity.
Hypericin, a constituent of Hypericum, possesses pronounced antiviral and antineoplastic activity. |
Gale Maleskey
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 Turning On the Light
St. john's wort is widely available as a tincture and capsules. Look for a standardized extract that contains 0.3 percent hypericin, which approximates the standard used in Germany and in many of the medical studies. A typical dose of the extract is 300 milligrams three times a day.
Because of its mild action, St. john's wort takes more time to build up in your system than prescription antidepressants do, says Dr. Merrell. "It will take somewhere between four and six weeks before you'll start noticing any effect. |
| For prevention, take one 300-milligram capsule daily during times of stress or as soon as you feel a cold sore coming on, he says.
St. john's wort has strong antiviral properties that may help to prevent the herpesvirus from replicating. In fact, this herb's antiviral activity is so significant that high concentrations of it have decreased HIV (the virus that causes AIDS) in a laboratory setting. The active ingredients that possess these antiviral properties are hypericin and pseudohypericin.
During a cold sore outbreak, take one 300-milligram capsule of St. john's wort daily, says Dr. Traub. |
Stephen Cummings and Dana Ullman
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 Hahnemann's calcium suphide* Hydrastis (Hydrastis)—goldenseal
Hypericum perforatum (Hypericum or Hyper.)—St. john's wort (internal and external preparations) * Ignatia imara (Ign.)—St. Ignatius bean* Ipecacuanha (Ipec.)—ipecac root* Iris versicolor (Iris.)—blue flag Kali bichromium (Kali bi.)—bichromate of potash* Kreosotum (Kreos.)—beechwood kreosote
Lachesis (Lach.)—venom from the bushmaster or surucucu snake* Ledum palustre (Ledum.)—marsh tea* Lycopodium (Lyc.)—club moss*
Magnesium phosphorica (Mag. phos.)—phosphate of magnesia* Mercurius (Merc.)—quicksilver or mercury* Mezereum (Mez. |
Dr. Julian Whitaker
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| In reality, they are caused by severe depression.
St. john's wort (Hypericum perforatum) is a safe, natural therapy that has been demonstrated to be an effective treatment for depression. It is as effective as prescription antidepressants, according to some studies. The British Medical Journal published a 1996 analysis of twenty-three clinical trials on St. john's wort, involving 1,757 patients. The trials demonstrated that the herb was three times as effective as a placebo in relieving the symptoms of depression. Even more important, in eight of these studies comparing St. |
Larry Trivieri, Jr.
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 ST. john's wort (HYPERICUM PERFORATUM)
A remedy long used as an anti-inflammatory, wound-healing nervine valued for its mild sedative and pain-reducing properties, St. john's wort has recently regained medical attention. Taken internally, it has traditionally been used to treat neuralgia, anxiety, tension, and similar problems. In addition to neuralgic pain, it will ease fibrositis, sciatica, and rheumatic pain.102 It is especially regarded as an herb to use in the case of menopausal changes triggering irritability and anxiety. |
| HERBS: • Mix equal parts willow bark and St.John's wort tincture and take Vi teaspoon three times a day. • Massage with warm St. john's wort oil will help alleviate pain. • Black cohosh, chamomile, fenugreek, juniper berries, mugwort, parsley, rosemary, skullcap
HOMEOPATHY: Colocynth, Viscum album, Lachesis, Rhus tox., Aconite, Arsen alb., Lycopodium, Magphos., Ruta grav. Dr. Chaitow recommends Atropa belladonna 6X for neuralgia.
HYDROTHERAPY: • Contrast application (apply daily). • According to Dr. Chaitow, a neutral bath (body temperature) has a profoundly calming effect. |
Robert S. McCaleb, Evelyn Leigh, and Krista Morien
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 Major Constituents
Hypericin, hyperforin, pseudohypericin, flavonoids, xanthones, essential oil
Safety
St. john's wort is well tolerated by most people, and there are no reports of major side effects with recommended doses. Side effects are rare, and those that do occur are generally mild.
• Side effects: In clinical trials, only a few people experienced minor side effects, such as mild stomach upset. A drug-monitoring study that evaluated the safety and effectiveness of St. john's wort in 3,250 people documented a side effect rate of only 2.4 percent. |
volker schulz and Rudolf Hansel
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| This latter cost difference is reflected in per-day treatment costs, which range from approximately 40 cents (St. john's wort and amitriptyline) to $2 (alpha-2-antagonists and SSRIs). The health insurance funds in Germany spent almost $500 million for synthetic antidepressants alone in 2001. This is more money than was spent for all phytomedicines that were prescribed during the same year (Schwabe and Paffrath, 2002).
Unfortunately, antidepressants are not an isolated case. As we shall see in Sect. 2.1. |
Ralph W. Moss PhD
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 Others are plausible entries, such as
St. john's wort.
Vitae Elixxir Ingredients
Scientific Name Common Name AHPA
Chlorophyllin (plant component) —
Sanguinaria canadensis Bloodroot 2b, 2d
Impatiens pallida Jewelweed —
Hydrastis canadensis Goldenseal 2b
Ferula galbaniflua Galbanum 2b, 2d+
Hypericum perforatum St. john's wort 2d
Rubus villosus American blackberry 1
Fumaria officinalis Fumitory —
Frasera carolinensis American columbo —
Allicin (ingredient in garlic) —
Allium sativum Garlic 2c
Trace Elements: Zinc, Potassium, Barium, Iron, Sodium, Calcium, Copper. |
volker schulz and Rudolf Hansel
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| Hypericum Depression Trial Study Group: effect of Hypericum perforatum (St. john's wort) in major depressive disorder. A randomized controlled trial. JAMA 287:1807-14,2002.
IfD-Umfrage 1016 (2002) Institut fur Demoskopie, Allensbach/Germany, Allensbacher Archiv.
Jiittner G (1983) Therapeutische Konzepte und soziales Anliegen in der friihen Krauterheilkunde. In: lmhof AE (ed.) Der Mensch und sein Korper. Beck, Munich, 118-130.
Keller K (1996) Herbal medicinal products in Germany and Europe: experiences with national and European assessment. Drug Inform J 30: 933-948. |
Donald R. Yance, j r.,C.N., M.H., A.H.G., with Arlene Valentine
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| The nervous system must be healed before any other aspect of healing can take place; this is why pulsatilla is a friend (more like an angel) to many of the cancer patients I see.
St. john's wort [Hypericum perforatum)
St. john's wort is a wonderful nervine, especially indicated for mild forms of depression with poor circulation and nerve injury. It can be used both internally and externally for nerve trauma. A specific for postoperative brain tumor surgery, it helps in three different ways:
1. It promotes healing from trauma and inflammation.
2. It helps with postoperative depression.
3. |
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